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Italian Penicillin Soup Recipe

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A comforting Italian twist on classic chicken soup, this Italian Penicillin Soup is filled with tender chicken, aromatic herbs, fresh lemon, and small pasta. It’s nourishing, flavorful, and perfect for when you need something cozy, healing, and satisfying.

  • Total Time: 50 minutes
  • Yield: 6 servings

Ingredients

Base Ingredients:

2 tablespoons extra virgin olive oil

1 large onion, diced (about 1 cup)

3 medium carrots, sliced into rounds

3 celery stalks, chopped

4 garlic cloves, minced

8 cups low-sodium chicken broth (or vegetable broth for vegetarian option)

1 whole chicken breast, bone-in and skin-on (about 1 pound)

2 bay leaves

1 cup small pasta (ditalini, orzo, or small shells)

Seasonings & Aromatics:

1 teaspoon dried oregano

½ teaspoon dried thyme

¼ teaspoon red pepper flakes (optional)

Salt and freshly ground black pepper, to taste

2 tablespoons fresh lemon juice

¼ cup fresh parsley, chopped

Garnishes & Finishing Touches:

Freshly grated Parmigiano-Reggiano cheese

Extra virgin olive oil for drizzling

Crusty Italian bread for serving

Instructions

  1. Heat olive oil in a large soup pot over medium heat.
  2. Add diced onion, carrots, and celery, cooking for 5–7 minutes until vegetables begin to soften.
  3. Stir in garlic, oregano, thyme, and red pepper flakes, cooking for another minute until fragrant.
  4. Pour in chicken broth and add bay leaves. Place chicken breast in the pot.
  5. Bring to a gentle boil, then reduce heat and simmer for 25–30 minutes until chicken is cooked through.
  6. Remove chicken, shred the meat, and discard bones and skin.
  7. While shredding chicken, add pasta to the pot and cook until al dente.
  8. Return shredded chicken to the soup, stir in lemon juice and parsley, and season with salt and pepper to taste.
  9. Remove bay leaves, drizzle olive oil over the top, and ladle into bowls.
  10. Finish with freshly grated Parmigiano-Reggiano and serve with crusty bread.

Notes

Use boneless chicken or rotisserie chicken for quicker prep.

Add cannellini beans or chickpeas for extra protein.

Make vegetarian by using vegetable broth and skipping chicken.

Stir in spinach or kale for added nutrients.

Freeze without pasta for best texture; add freshly cooked pasta when reheating.

  • Author: Madelynn
  • Prep Time: 15 minutes
  • Cook Time: 35 minutes
  • Category: Soup
  • Method: Stovetop
  • Cuisine: Italian
  • Diet: Low Fat

Nutrition

  • Serving Size: 1 bowl (about 2 cups)
  • Calories: 280
  • Sugar: 5g
  • Sodium: 680mg
  • Fat: 9g
  • Saturated Fat: 2g
  • Unsaturated Fat: 7g
  • Trans Fat: 0g
  • Carbohydrates: 25g
  • Fiber: 3g
  • Protein: 25g
  • Cholesterol: 65mg